Potential Therapeutic Targets for PPAR after Spinal Cord Injury
نویسندگان
چکیده
منابع مشابه
Potential Therapeutic Targets for PPARγ after Spinal Cord Injury
Traumatic injury to the spinal cord results in multiple anatomical, physiological, and functional deficits as a result of local neuronal and glial cell death as well as loss of descending and ascending axons traversing the injury site. The many different mechanisms thought to contribute to protracted secondary cell death and dysfunction after spinal cord injury (SCI) are potential therapeutic t...
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The ubiquitin-proteasome system (UPS) is a crucial protein degradation system in eukaryotes. Herein, we will review advances in the understanding of the role of several proteins of the UPS in Alzheimer's disease (AD) and functional recovery after spinal cord injury (SCI). The UPS consists of many factors that include E3 ubiquitin ligases, ubiquitin hydrolases, ubiquitin and ubiquitin-like molec...
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ژورنال
عنوان ژورنال: PPAR Research
سال: 2008
ISSN: 1687-4757,1687-4765
DOI: 10.1155/2008/517162